Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | (Depression) Mental health problems ever diagnosed by a professional__20544-both_sexes-11 |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL18402, MIXED, INCL. MAP KINASE ACTIVITY, AND PROTEIN TYROSINE|THREONINE PHOSPHATASE ACTIVITY |
| Enrichment Score (ES) | 0.6194501 |
| Normalized Enrichment Score (NES) | 1.5180827 |
| Nominal p-value | 0.001 |
| FDR q-value | 0.15783322 |
| FWER p-Value | 0.148 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | PPM1A | 29 | 2.841 | 0.1459 | Yes |
| 2 | DUSP8 | 189 | 1.924 | 0.2369 | Yes |
| 3 | MAP3K1 | 196 | 1.906 | 0.3356 | Yes |
| 4 | MAP2K4 | 567 | 1.389 | 0.3868 | Yes |
| 5 | PTPRR | 656 | 1.331 | 0.4510 | Yes |
| 6 | MAPKAPK3 | 1007 | 1.147 | 0.4908 | Yes |
| 7 | MAPK8IP3 | 1009 | 1.146 | 0.5503 | Yes |
| 8 | MAPKAPK5 | 1490 | 0.984 | 0.5743 | Yes |
| 9 | MAPK11 | 2627 | 0.759 | 0.5496 | Yes |
| 10 | MAPK12 | 2779 | 0.736 | 0.5793 | Yes |
| 11 | MAPK8 | 3244 | 0.673 | 0.5881 | Yes |
| 12 | PTPN7 | 3424 | 0.650 | 0.6117 | Yes |
| 13 | MAPKAPK2 | 3845 | 0.605 | 0.6195 | Yes |
| 14 | MAPK9 | 4931 | 0.509 | 0.5846 | No |
| 15 | MAPK13 | 6642 | 0.392 | 0.5085 | No |
| 16 | DUSP3 | 7671 | 0.339 | 0.4681 | No |
| 17 | MAPK4 | 8683 | 0.294 | 0.4263 | No |
| 18 | DUSP7 | 8906 | 0.285 | 0.4285 | No |
| 19 | DLG1 | 9594 | 0.260 | 0.4033 | No |
| 20 | HSPB1 | 9713 | 0.256 | 0.4099 | No |
| 21 | DUSP4 | 10600 | 0.226 | 0.3717 | No |
| 22 | MAP2K3 | 10741 | 0.221 | 0.3753 | No |
| 23 | MAP2K6 | 10966 | 0.213 | 0.3737 | No |
| 24 | MAPK14 | 15333 | 0.083 | 0.1316 | No |
| 25 | PTPN5 | 16626 | 0.041 | 0.0608 | No |
| 26 | PTPN3 | 16647 | 0.040 | 0.0618 | No |
| 27 | MAPK6 | 16831 | -0.000 | 0.0514 | No |
| 28 | VRK3 | 16915 | -0.000 | 0.0467 | No |
| 29 | DUSP16 | 16953 | -0.000 | 0.0446 | No |
| 30 | HSPB2 | 17440 | -0.000 | 0.0172 | No |
